Introduction
Malignant brain tumor - Unmet Medical Needs
- Incurable disease with the highest mortality rate in the clinical array of brain tumors.
- Curative treatment is impossible - Because it grows invasively as if it penetrates the brain and cannot be removed completely, drug reatment and radiation therapy are essential to remove the remaining tumor after surgery.
- Limitations of anticancer treatment due to pathological characteristics - Lack of drug treatment efficacy due to the blood-brain barrier whose more than 98% of existing drugs cannot penetrate.
- Diversity of molecular biological properties according to brain tumor internal location and time and overexpression of multi-drug resistance gene
Proposed NtoB technology for brain cancer treatment
- General therapy

- Our approach
